I joined the Sachse lab as a postdoc in April 2020 to work on the molecular structure and function of membrane-active proteins from cyanobacteria.
For my Bachelor thesis (2014) in Biomedical Chemistry at JGU Mainz, I worked on the lipid interaction of the Phage shock protein A (PspA), a bacterial protein, which is involved in membrane protection. In 2016 I finished my Master´s degree in Biomedical Chemistry at the JGU Mainz. For my Master thesis in the lab of Dirk Schneider, I analyzed the impact of divalent cations, especially Mg2+, on the structure and stability of the Inner membrane-associated protein of 30 kDa (IM30), a membrane fusion protein from plants, algae, and cyanobacteria, using Fluorescence Spectroscopy, CD-Spectroscopy, and Isothermal Titration Calorimetry.
For my PhD (2019), I was granted with a Max Planck Graduate Center (MPGC) fellowship and worked in close collaboration with the lab of Dirk Schneider and Eva Wolf (JGU Mainz) as well as Hans-Jürgen Butt and Stefan Weber from the Max Planck Institute for Polymer Research (MPI-P). In my PhD project, I focussed on the analysis of supercomplex formation and membrane interaction of IM30 and PspA, using in situ Atomic Force Microscopy, Electron Microscopy, Small-Angle X-ray Scattering, Hydrogen-Deuterium Exchange, CD-Spectroscopy, Fluorescence Spectroscopy and Chromatographic methods.
Phone: +49 2461 61-3130