Sachse group in the press

A New Tool for Cryo-Electron Microscopy

Jülich, 7 September 2022 – Researchers at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf led by Prof. Dr. Carsten Sachse are using cryo-electron microscopy, or cryo-EM for short, to make biomolecules visible at the atomic level. In a paper now published in the journal Nature Methods, they present a new method that combines cryo-EM with a method otherwise used in materials research. The results are also presented and classified in a Nature Briefing.

Artistic Rendering of scanning transmission electron microscopy (STEM) approach: a small electron beam rasters over the sample in small steps to illuminate the snap frozen biomolecules in ice.

Membrane Proteins of Bacteria and Humans Show Surprising Similarities

Jülich/Mainz, 24 June 2021 – The cells of simple organisms, such as bacteria, as well as human cells are surrounded by a membrane, which fulfills various tasks including protecting the cell from stress.

Atomic cryo-electron microscopic structure of PspA.

Cryo-Electron Microscopy Makes Structure of Important Membrane-deforming Proteins Visible

Jülich/Heidelberg, 19 August 2020 – Viruses multiply in the human body by hijacking the functions of cells and using them for their own purposes. Ebola, HIV and other viruses use, among other things, the so-called ESCRT-III complex for this purpose. In healthy cells, this intricate structure…

Structure of a double-stranded ESCRT-III polymer.

How Cells Stay Clean and Tidy

Jülich, 23 January 2020. Tidying up and throwing away unwanted items is currently very much in vogue and can even, according to the author of a current bestseller, change lives. Without a doubt, regular clear-outs are also vital for cells…

Helical assembly structure of autophagy receptor p62/SQSTM1.

Forschungszentrum Jülich GmbH, Wilhelm-Johnen-Straße, 52428 Jülich, Germany
c.sachse[at]fz-juelich.de
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