Prof. Dr. Carsten Sachse

Carsten Sachse
Head Structural Biology (ER-C-3)

I am the director of the newly founded Ernst-Ruska-Centre 3 for Structural Biology at the Forschungszentrum Jülich. I was a group leader at the EMBL from 2010 – 2018. I got in touch with electron cryomicroscopy by studying amyloid fibrils in the groups of Marcus Fändrich(now in Ulm, Germany) and Niko Grigorieff (now at Janelia Farm, USA).For my postdoctoral period, I went to the MRC Laboratory of Molecular Biology(Cambridge, UK) to work with Richard Henderson and Roger Williams. In the last few years, we set up a group to study the mechanisms of autophagy by electron cryomicroscopy. Traditionally, I have been interested in the advancement of high-resolution single-particle EM with a particular focus on helical reconstruction. These developments have led to our recent helical processing software package Spring. More recently, we became interested in improving means of cryo-EM map interpretation by atomic models.


Forschungszentrum Jülich GmbH
52428 Jülich

Ernst Ruska-Centre
Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons 
ER-C-3: Structural Biology
52425 Jülich


Phone: +49 2461 61-2030